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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7b003f1c8343505f1b7722f6d23d138a8d7691fe751acaf689ca4fb4997d0d4' 
  AND token = 'onuRFl5XCIfbWORZD+IvHltEoyqCuOYVwsbRsN5dIaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}