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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dfdfdaee72b72b7532f9ec2809b1e5a219c9378a084ad5cbb3a284436f6a7e0' 
  AND token = '/gDX8DQG8kJ2hsGfWacToEctqo5rPyt+dz89X+C1dWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}