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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c503ff1f4ddbf2cc43dfdc64cd4c2cdcd44c2f802171cdca54a41b9bd65951d9' 
  AND token = 'EwhSM7+lclIdS/BUT0qfuOTsV1rN4dMKUXUxbs1nDk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}