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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '640c5d18a9f5077d561f8e93aa555e4793721d9e1cbaeeea0e1207679979c431' 
  AND token = 'zhqkZj3XrLPYLg0wFwF6tdtWFe5DOt8G7D8g6bYHJR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}