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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a11b1abf40f46dbf896c67c1c8d0c74a26dd54f54e3acdac60ce1edc0e9dcc' 
  AND token = 'D1+kSk0WvoJZL+RxtICGoPVJSVoq5lWat+FNHYhN9LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}