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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33702bbee569846761a5088c46c0c830d736401c15dea630d28d35b2efcff20' 
  AND token = 'bT1HYj3EYP4Oq8j9oMnILjIFbQJh5Min1H9xzB1EIm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}