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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa3cf35c10fa4ac22d8eee559138a2b4778b2add504682a8fb72312573b5d5a' 
  AND token = 'ds85Nyq+YKQz/zMxb4LNvEb9LuoJdaQLXwOnepqyoqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}