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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76fc2354d468bc81bb44bb2b25a4f46df65b291c8d59d5e4fbd0770ab833cec8' 
  AND token = 'QoBkiCRyuLJuyj4x+UPHiDLkOA0YK8Evbb7hJKOC27M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}