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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09d821127822380a5b545a372b224b220283ab86198ef0f31e1c4f0f6d076dda' 
  AND token = 'UPsgAljyIXM2+8IO7vpTaQA4b+8r8LY/aGoRrAkzJXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}