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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53aaf8a1b4441cb66a507a4f618173c7ea9997a8fe903aeab20db170300a8a3c' 
  AND token = 'lqrEz7KdmC2sk6BBPD+Ri8N1Kt0rRpDEmy4l0Nzxzb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}