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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5c4a783ed1b63167cf3ffc31aae5b88d3bcf2f2a7a93dc5215340591838be2' 
  AND token = 'iOk4zdMgTtq1BaQOTJIc8IgSjLsaeG6Us1aO5AcDcyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}