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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e750f97409df4b28726a1e0abb10c5e6c31c21eafb3269f7039bcc6c26f962f' 
  AND token = 'l8zB5w8woON8ed5qEYQJHxE9M9K6GD2xEfyOF+Gzxb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}