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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab3748639846822a11d402a59d14334dc0f57b20fa7274aa9cab49422d1200e' 
  AND token = 'CW6JHM8PldUgCO/JenjL7PsrrEsCVN28rPX/LTAs+u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}