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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4807d3b846ac0f024437764ff3bca085788168674378885cac5d632716460c78' 
  AND token = 'F1huP7K0BA+d7OZSKKON/yRWSTN3oOlRZxspBkZQ47I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}