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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d504e5abf732cad52ce058fa336e7f7958ec919ff8dab7fa69ce10122a11799' 
  AND token = '0uUVt5gR3nNXF2EogQuOcsCaLujfpqqpD56XMWGlbgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}