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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3b68c127c95834988ba3f774ef5cf5d38d36d41142a8acd46e32e9e5024dfb' 
  AND token = 's6NnU6V1Mmj0HY4DcQqcHE9bHY/OML9fTAJsTrZSWKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}