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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8cf5779d933491768d83827e8ca1dc9ba0f411fe05ad0ac4260e850d6d1a81' 
  AND token = '0cQtLS+ujprm3TN/L1rW/EN02komN8lpLwNw1LzBJfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}