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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef0b25fc60db3f708725e660c11fc0e73fa2c7568d36242ea74318d70880a3e2' 
  AND token = 'x5XIpP3CXBxcvEkeJgJzaC/pIg7gpXWBDMz7D4/ZgSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}