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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3564a29b12c83589d818dbf37ca405adba427f690f611f1207a835966cf9e4f2' 
  AND token = 's1kiCzxq1rCa4Nbpkj9WQXJzmMw41S0GQTx+43b0Slw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}