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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601a1c58b140f4c75a17dd188a6305c44bfce4a7f8d60c8ace849ff8b92482e4' 
  AND token = 'r2skoGUVVQYml0WSAikxThDPmKvgjeKAAdeibtO6Bzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}