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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84ec3d8ece8d74f0abf26617a5d5e1fd0460fc53738f235710b3017d65319fd7' 
  AND token = 's7M/BQNFLqDsjd0mUkQuSd7QiQ8UT72hfgD+7MR8ikU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}