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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72e9e44cf9bdc1c034aa6c25424347e9240ded1571122cebedc3c0efa92c24d' 
  AND token = 'c5G9do8QLLjEXkOvYx7uZs7IvzxGgQn6ZSOvDiSAU6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}