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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c680993d2eb47028cb31ae29224cfbbce442ddca9816a3aa7f99acb014938081' 
  AND token = '+TdUDsxZCwvxUIUy9B9SpFsqIOTn/L4q/MCO4wgRsKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}