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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f07f57c0a653ea1c4214c71a888e0bb844c324ec1c3b00a0bc67e408e44b82' 
  AND token = 'u67CdKg5dGm/RJ2cJPL9yOs7xxQ/EiSWJWk8T9PQycw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}