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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fbf6b57810e03c0d5cde96f0cd911a7a69456057277060ad3ca87565c84a36e' 
  AND token = '4/g/YmbOdqf9wbJmwUe/eSAgGw19hQjUG1LI10De/gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}