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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a43b5c428624f78ef860690cd65f915d938b4cb20678fb5c77ac173773efe2' 
  AND token = 'ueX+jujev93RdXZA7PEmg/F49MXsr3sDXakrrZu4SKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}