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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4a7a29a2dd33d69b5b08679d06737742e03842ca29eef7fbb27b29d249e2056' 
  AND token = 'f2LUDei+2i9D1iZ0IZebwG42yHSAUDGR5UaY5SEGjWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}