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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049b6b16c0d55dd7c719a737a2a6025ec4e2703817cbf72a4e43809cd1d080bf' 
  AND token = 'jVELHyy4CsnLkMTmX4keFUwdBxmJGD194xoRZDuTj1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}