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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b780dff9d8db6d57607c7fdd6a54e98de91631c283b63c498a60aa72ce170a71' 
  AND token = '+rErKKiMhV5hytVbo8okjoV4mhBQQS8jCS88k8wL2VY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}