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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee84d2c21b9ce3be64d6da356a1311baa3c4b9d6fc6066e56e04125e767d2116' 
  AND token = 'sFMPgTC+in1r/3pQgQi7bWHLy0gWlFNp7lQ+m9sE+Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}