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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f48028e6ac459750d6c0d86efb42b23f702ef678f8733b86207f4f3f10321f42' 
  AND token = 'M2CVaurxDHVUl7pe6Qj97+ApdtVe3I1d6Xmi3vzxXnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}