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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e298b4ccc48eb9e6d7d5648e4d3532c4826bf75f1876e8350ac5b12e66e78a' 
  AND token = 'V5LSdJNvWEWl8mecIxqqQPTtY4g8gXJ2h2RYoxsZ9Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}