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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8256227a93c5dd7e44914135e072db5669f7b1fb58be3e214b3c74c4a857bd' 
  AND token = 'MkyYUEo1p0ep13A/znexXIHTsoZ2QChXDotClByXjFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}