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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e46987799805926bc77d9ef50a2e83bdff7f93b760271f5dc06fcf651e8fef' 
  AND token = '7kIsb/FnazUWLf87sRDzrhFO9n1xyCZuOI39WS2wMrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}