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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec48775b0fb6fb3d808727df1976fe8e662445c79d59d1fdc583d47c46a5862c' 
  AND token = 'dR40D82mWaKDcrc5K+n9OzTWsAtFU49wry9aQTH36Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}