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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '994c9e38815174a800555bbbba5266e716797aeb276b63b1b5186d1949f45f52' 
  AND token = 'UgWDnhBc+j2tU0j6eseFn/mnSMYh5GAZp5EILKPZddE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}