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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dca43512f72d8ca8301526f6861d1e27176360659e220013c5c6e6b06b8b3ed' 
  AND token = 'MpI4p8ncKX7087JU+NpvoLU+9tXVabemJhBpaDMQBQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}