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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709b30d1421bb01032995e971964e7ab4a38fca0d614864ad597ebe174fdbf7b' 
  AND token = 'sJrKxPr9O7fPPWD0PEDN0QlXj2IWg3qRPQ9PI4suuFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}