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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1814a396fed4568fbb3c0664f8195617ffb49030aff66ccf16efa938debba0' 
  AND token = 'VURNDAYRS5B1rMatqg1nW50n5GLb/KXihYoIGDoBrxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}