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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4d4526cd8898488e8bdf6c54d019b022ab4c50dd7ab165cf95f0b55cd09d27' 
  AND token = '6i7NsUgdYF3Hh/hOK/6MFskingqXzCdPOjehyBr9/R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}