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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95bc2b44f55866cbae7e7bf9282474d0de2ba608592fe1556f526fc39c4dbfe0' 
  AND token = 'aqf0TFIQxte/wrDRdpTPtkdfB04W6vUQuyvPbEV31oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}