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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd5f6fed14f4f6d92ec84a5c9dc28dc80ac164964076b7face54df1032a209a5' 
  AND token = '2uZBkmuzEUTj5LC6wmKtjspLBRPFkAJ8B1zdz0Gc0cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}