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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '388d19acb774a4722c0e815c7550772b4ee689463b0f343f26f73351feba61d9' 
  AND token = 'rdxYL0vvMwUPVWQ2IaeFtx9UVtGec7/WkXdSJkUwdUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}