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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491e9f60ca793db1518c4b7e3f9308c4b9d9c4819eaafb00433caeb44e0197e0' 
  AND token = 'vu+g/+MeKcm+E2s6spXHecyx9X+dAz6zkCBN0PrXG1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}