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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7812c68935b78ee3d810c186ae5ab1e67f774c2e2e6c21809036439d8fb54ec3' 
  AND token = '5axivilOUtCKNpiR9jXl0vsabxxZezTLmgwYRU8UvNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}