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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc51a1f325688f31110722d5e289ba56c109e1722def4d564d7b6496074068f6' 
  AND token = 'EI57lAr0VTodZBbbRwVZTsCTrIicAdWOpNuyRZRgFkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}