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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ad7bc83c7da11a26f1ba54874abb566531a79cdccf4ebca219023698a9c689' 
  AND token = '0T8u26cCc67FW/1fKiat6/QdpONe/NKosAOqCac3gyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}