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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451cd3ff54bb7be88706b096b89b4a2d36c557c933149486d7de6b9d2069f26b' 
  AND token = 'qa5Pe7Dj6fpL2yqqdKDJ0NK6lawIzqjti43Vod/Wt1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}