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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8e79780e71b06ff0d0e75ba951c1abb38f38728978318fa85aec25bd3cc306' 
  AND token = 'RGrQ2bjXunvU+X6J3M2VHZQv0N1tEab4ViRn3QikvQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}