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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cf76d5638dc860bd302e7db32d6e42fde296756b594699039d5e6078f54f48' 
  AND token = 'W8GCUV0hstOZbYowz/w30xCx7djpSfxRSfEZy1IEL/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}